Different
people have different pattern of bone reformation and resorbing, this is the
reason why doctor are persuaded that there are different causes of osteoporosis
possible.
Any
significant changes in such important chemicals as estrogen, testosterone,
parathyroid hormone, vitamin D, calcium, as well as blood factors, may result
in osteoporosis.
Sex
hormones are among the usual osteoporosis causes
both in men and in women. After the menopause a substantial and sudden decrease
of bone density occurs. The responsible chemical for this process is estrogen,
because the production of it stops.
For men
testosterone is the most important hormone, which is converted into estrogen in
different parts of a man’s body, including the bones. Studies have shown that
the loss in both estrogen and testosterone in elderly men contribute to bone
loss, and they both seem to be integral to bone function.
A low
vitamin D and calcium level is also what causes
osteoporosis. Vitamin D is the vitamin that is much like a hormone. It
is responsible for normal absorption of calcium and for the bone growth as
well. If there is a vitamin D deficiency, the calcium absorption becomes
impaired, which triggers an increase in parathyroid hormone levels.
Parathyroid
gland produces the parathyroid hormone. On the thyroid gland surface four
smaller glands are located; these glands are the most significant instruments
in regulating the levels of calcium in blood. If the level of calcium is low,
the glands stimulate a higher production of parathyroid hormone. It increases
then the calcium levels in blood, which may result in bone loss.
Genetic
factors are also the known causes of osteoporosis. If your parents or siblings
have been diagnosed with osteoporosis, of if there is a family history of bone
fracture; you are more likely to develop this condition too.
Certain
drugs, such as corticosteroid ones, that are being commonly used to treat
different types of disorders may reduce bone mass in men and women. It is not
proven yet whether inhaled steroids are as dangerous, but some of the studies
show that they may result in substantial bone loss when taken for long periods
of time and at high doses. Children, who are on inhaled steroids, such as to
treat asthma, may experience a temporary impairment in growth, but they do not
seem to have the bone loss risk.
Depending
on the type of the disorder, diuretics may also be the causes of osteoporosis.
Diuretics are used to treat high blood pressure. Such loop diuretic as
furosemide, or Lasix may increase the excretion of calcium in the kidneys, and
as a result cause bone loss. However, thiazide diuretics, have an opposite
effect, they protect bones from thinning, but this effect only takes place
while the medication is taken, once it’s stopped, no such effect is further
present.
The loss of
bone density may also be provoked by hormonal contraceptives that use estrogen
and progestin, such as Depo-Provera injection, for instance.
And
finally, such conditions as alcoholism, diabetes, hyperthyroidism, epilepsy,
and a number of others may also increase the chances of developing osteoporosis.
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